Circular antisense oligonucleotides inhibit growth of chronic myeloid leukemia cells.

BACKGROUND: Antisense represents a conceptually powerful method for regulating gene expression. However, antisense oligonucleotides developed to date manifest two serious limitations-nuclease susceptibility and nonspecific hybridization. Circular oligonucleotides may be superior to conventional line...

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Hauptverfasser: Rowley, P. T., Kosciolek, B. A., Kool, E. T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Feinstein Institute for Medical Research 1999
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230474/
https://ncbi.nlm.nih.gov/pubmed/10602778
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