Herpes simplex virus (HSV)-mediated ICAM-1 gene transfer abrogates tumorigenicity and induces anti-tumor immunity.

BACKGROUND: Costimulatory and cellular adhesion molecules are thought to be essential components of antigen presentation in the immune response to cancer. The current studies examine gene transfer utilizing herpes viral amplicon vectors (HSV) to direct surface expression of adhesion molecules, and s...

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Main Authors: D'Angelica, M., Tung, C., Allen, P., Halterman, M., Delman, K., Delohery, T., Klimstra, D., Brownlee, M., Federoff, H., Fong, Y.
Format: Artigo
Sprog:Inglês
Udgivet: The Feinstein Institute for Medical Research 1999
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230459/
https://ncbi.nlm.nih.gov/pubmed/10551902
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