Combination vascular delivery of herpes simplex oncolytic viruses and amplicon mediated cytokine gene transfer is effective therapy for experimental liver cancer.

BACKGROUND: Herpes simplex type I (HSV)-based vectors have been used experimentally for suicide gene therapy, immunomodulatory gene delivery, and direct oncolytic therapy. The current study utilizes the novel concept of regional delivery of an oncolytic virus in combination with or serving as the he...

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Bibliographische Detailangaben
Hauptverfasser: Zager, J. S., Delman, K. A., Malhotra, S., Ebright, M. I., Bennett, J. J., Kates, T., Halterman, M., Federoff, H., Fong, Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950059/
https://ncbi.nlm.nih.gov/pubmed/11591892
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