Herpes simplex virus (HSV)-mediated ICAM-1 gene transfer abrogates tumorigenicity and induces anti-tumor immunity.

BACKGROUND: Costimulatory and cellular adhesion molecules are thought to be essential components of antigen presentation in the immune response to cancer. The current studies examine gene transfer utilizing herpes viral amplicon vectors (HSV) to direct surface expression of adhesion molecules, and s...

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Hauptverfasser: D'Angelica, M., Tung, C., Allen, P., Halterman, M., Delman, K., Delohery, T., Klimstra, D., Brownlee, M., Federoff, H., Fong, Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Feinstein Institute for Medical Research 1999
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230459/
https://ncbi.nlm.nih.gov/pubmed/10551902
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