Beta-cell apoptosis in an accelerated model of autoimmune diabetes.

BACKGROUND: The non-obese diabetic (NOD) mouse is a model of human type 1 diabetes in which autoreactive T cells mediate destruction of pancreatic islet beta cells. Although known to be triggered by cytotoxic T cells, apoptosis has not been unequivocally localized to beta cells in spontaneously diab...

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Detalhes bibliográficos
Main Authors: Augstein, P., Stephens, L. A., Allison, J., Elefanty, A. G., Ekberg, M., Kay, T. W., Harrison, L. C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute for Medical Research 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230405/
https://ncbi.nlm.nih.gov/pubmed/9742505
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