Alterations of p16-pRb pathway and chromosome locus 9p21-22 in sporadic invasive breast carcinomas.

The p16-pRb pathway represents a vital cell-cycle checkpoint. In the present study we investigated the alterations of this G1-phase protein pathway using immunohistochemical and molecular methods in a series of 55 breast carcinomas and correlated the findings with clinicopathological features of the...

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Main Authors: Gorgoulis, V. G., Koutroumbi, E. N., Kotsinas, A., Zacharatos, P., Markopoulos, C., Giannikos, L., Kyriakou, V., Voulgaris, Z., Gogas, I., Kittas, C.
Formato: Artigo
Idioma:Inglês
Publicado: The Feinstein Institute for Medical Research 1998
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230392/
https://ncbi.nlm.nih.gov/pubmed/9990866
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