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Transgenic mice expressing Shb adaptor protein under the control of rat insulin promoter exhibit altered viability of pancreatic islet cells.

BACKGROUND: The Src-homology 2 domain-containing adaptor protein Shb was recently cloned as a serum-inducible gene in the insulin-producing beta-TC1 cell line. Subsequent studies have revealed an involvement of Shb for apoptosis in NIH3T3 fibroblasts and differentiation in the neuronal PC12 cells. T...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Welsh, M., Christmansson, L., Karlsson, T., Sandler, S., Welsh, N.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Feinstein Institute for Medical Research 1999
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230291/
https://ncbi.nlm.nih.gov/pubmed/10404514
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