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Characterization and cell distribution of polycystin, the product of autosomal dominant polycystic kidney disease gene 1.
BACKGROUND: In a majority of cases, autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations within a putative open reading frame of the PKD1 gene. The encoded protein, polycystin, is predicted to span the plasma membrane several times and contains extracellular domains, suggestiv...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Feinstein Institute for Medical Research
1996
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2230129/ https://ncbi.nlm.nih.gov/pubmed/8972485 |
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