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Interleukin-4 receptor expression on AIDS-associated Kaposi's sarcoma cells and their targeting by a chimeric protein comprised of circularly permuted interleukin-4 and Pseudomonas exotoxin.

BACKGROUND: AIDS-associated Kaposi's sarcoma (AIDS-KS) represents one of the most common malignancies associated with human immunodeficiency virus infection. To target effective therapeutic agents to AIDS-KS, we have identified a new target in the form of interleukin-4 receptors (IL-4R). MATERI...

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Main Authors: Husain, S. R., Gill, P., Kreitman, R. J., Pastan, I., Puri, R. K.
Format: Artigo
Sprog:Inglês
Udgivet: The Feinstein Institute for Medical Research 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230073/
https://ncbi.nlm.nih.gov/pubmed/9205948
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