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Hemoglobin switching in humans is accompanied by changes in the ratio of the transcription factors, GATA-1 and SP1.
BACKGROUND: Understanding the mechanism of developmental regulation of hemoglobin switching has scientific as well as clinical relevance because of the influence of fetal hemoglobin (HbF) production in adulthood on the clinical manifestation of thalassemia and sickle cell anemia. We have previously...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Feinstein Institute for Medical Research
1995
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2229915/ https://ncbi.nlm.nih.gov/pubmed/8529108 |
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