GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1

We investigated mechanisms underlying GATA-6-mediated transcriptional activation of the alveolar epithelial type I cell-enriched gene aquaporin-5 (AQP5). GATA-6 expression increases in alveolar epithelial cells in primary culture, concurrent with upregulation of AQP5 and transition to a type I cell-...

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Detalhes bibliográficos
Main Authors: Zhou, Beiyun, Francis, Tricia A., Yang, Hui, Tseng, Wanru, Zhong, Qian, Frenkel, Baruch, Morrisey, Edward. E., Ann, David. K., Minoo, Parviz, Crandall, Edward D., Borok, Zea
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Membrane Transporters, Ion Channels, and Pumps
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584994/
https://ncbi.nlm.nih.gov/pubmed/18768929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00120.2008
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