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Hemoglobin switching in humans is accompanied by changes in the ratio of the transcription factors, GATA-1 and SP1.

BACKGROUND: Understanding the mechanism of developmental regulation of hemoglobin switching has scientific as well as clinical relevance because of the influence of fetal hemoglobin (HbF) production in adulthood on the clinical manifestation of thalassemia and sickle cell anemia. We have previously...

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Bibliographic Details
Main Authors: Bacon, E. R., Dalyot, N., Filon, D., Schreiber, L., Rachmilewitz, E. A., Oppenheim, A.
Format: Artigo
Language:Inglês
Published: The Feinstein Institute for Medical Research 1995
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229915/
https://ncbi.nlm.nih.gov/pubmed/8529108
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