Hemoglobin switching in humans is accompanied by changes in the ratio of the transcription factors, GATA-1 and SP1.

BACKGROUND: Understanding the mechanism of developmental regulation of hemoglobin switching has scientific as well as clinical relevance because of the influence of fetal hemoglobin (HbF) production in adulthood on the clinical manifestation of thalassemia and sickle cell anemia. We have previously...

Full description

Saved in:
Bibliographic Details
Main Authors: Bacon, E. R., Dalyot, N., Filon, D., Schreiber, L., Rachmilewitz, E. A., Oppenheim, A.
Format: Artigo
Language:Inglês
Published: The Feinstein Institute for Medical Research 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229915/
https://ncbi.nlm.nih.gov/pubmed/8529108
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items