Effects of ACTH, dexamethasone, and adrenalectomy on 11β-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) gene expression in the rat central nervous system

Using a highly sensitive quantitative RT-PCR method for the measurement of CYP11B1 (11β-hydroxylase) and CYP11B2 (aldosterone synthase) mRNAs, we previously demonstrated that CYP11B2 expression in the central nervous system (CNS) is subject to regulation by dietary sodium. We have now quantified the...

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Bibliographic Details
Main Authors: Ye, Ping, Kenyon, Christopher J, MacKenzie, Scott M, Nichol, Katherine, Seckl, Jonathan R, Fraser, Robert, Connell, John M C, Davies, Eleanor
Format: Artigo
Language:Inglês
Published: BioScientifica 2008
Subjects:
Regular Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229629/
https://ncbi.nlm.nih.gov/pubmed/18252953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-07-0439
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