High glucose stimulates expression of aldosterone synthase (CYP11B2) and secretion of aldosterone in human adrenal cells

Aldosterone synthase is the key rate‐limiting enzyme in adrenal aldosterone production, and induction of its gene (CYP11B2) results in the progression of hypertension. As hypertension is a frequent complication among patients with diabetes, we set out to elucidate the link between diabetes mellitus...

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Bibliografische gegevens
Gepubliceerd in:FEBS Open Bio
Hoofdauteurs: Shimada, Hiroki, Kogure, Naotaka, Noro, Erika, Kudo, Masataka, Sugawara, Kaori, Sato, Ikuko, Shimizu, Kyoko, Kobayashi, Makoto, Suzuki, Dai, Parvin, Rehana, Saito‐Ito, Takako, Uruno, Akira, Saito‐Hakoda, Akiko, Rainey, William E., Ito, Sadayoshi, Yokoyama, Atsushi, Sugawara, Akira
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586344/
https://ncbi.nlm.nih.gov/pubmed/28904869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12277
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