High glucose stimulates expression of aldosterone synthase (CYP11B2) and secretion of aldosterone in human adrenal cells

Aldosterone synthase is the key rate‐limiting enzyme in adrenal aldosterone production, and induction of its gene (CYP11B2) results in the progression of hypertension. As hypertension is a frequent complication among patients with diabetes, we set out to elucidate the link between diabetes mellitus...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:FEBS Open Bio
Päätekijät: Shimada, Hiroki, Kogure, Naotaka, Noro, Erika, Kudo, Masataka, Sugawara, Kaori, Sato, Ikuko, Shimizu, Kyoko, Kobayashi, Makoto, Suzuki, Dai, Parvin, Rehana, Saito‐Ito, Takako, Uruno, Akira, Saito‐Hakoda, Akiko, Rainey, William E., Ito, Sadayoshi, Yokoyama, Atsushi, Sugawara, Akira
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586344/
https://ncbi.nlm.nih.gov/pubmed/28904869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12277
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