High glucose stimulates expression of aldosterone synthase (CYP11B2) and secretion of aldosterone in human adrenal cells

Aldosterone synthase is the key rate‐limiting enzyme in adrenal aldosterone production, and induction of its gene (CYP11B2) results in the progression of hypertension. As hypertension is a frequent complication among patients with diabetes, we set out to elucidate the link between diabetes mellitus...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FEBS Open Bio
Egile Nagusiak: Shimada, Hiroki, Kogure, Naotaka, Noro, Erika, Kudo, Masataka, Sugawara, Kaori, Sato, Ikuko, Shimizu, Kyoko, Kobayashi, Makoto, Suzuki, Dai, Parvin, Rehana, Saito‐Ito, Takako, Uruno, Akira, Saito‐Hakoda, Akiko, Rainey, William E., Ito, Sadayoshi, Yokoyama, Atsushi, Sugawara, Akira
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586344/
https://ncbi.nlm.nih.gov/pubmed/28904869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12277
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