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Block of Tetrodotoxin-resistant Na(+) Channel Pore by Multivalent Cations: Gating Modification and Na(+) Flow Dependence

Tetrodotoxin-resistant (TTX-R) Na(+) channels are much less susceptible to external TTX but more susceptible to external Cd(2+) block than tetrodotoxin-sensitive (TTX-S) Na(+) channels. Both TTX and Cd(2+) seem to block the channel near the “DEKA” ring, which is probably part of a multi-ion single-f...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kuo, Chung-Chin, Chen, Wan-Yu, Yang, Ya-Chin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 2004
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229605/
https://ncbi.nlm.nih.gov/pubmed/15226363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409054
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