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Effect of Na(+) Flow on Cd(2+) Block of Tetrodotoxin-resistant Na(+) Channels

Tetrodotoxin-resistant (TTX-R) Na(+) channels are 1,000-fold less sensitive to TTX than TTX-sensitive (TTX-S) Na(+) channels. On the other hand, TTX-R channels are much more susceptible to external Cd(2+) block than TTX-S channels. A cysteine (or serine) residue situated just next to the aspartate r...

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Autori principali: Kuo, Chung-Chin, Lin, Ting-Jiun, Hsieh, Chi-Pan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234463/
https://ncbi.nlm.nih.gov/pubmed/12149278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20018536
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