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Slow Inactivation Does Not Block the Aqueous Accessibility to the Outer Pore of Voltage-gated Na Channels

Slow inactivation of voltage-gated Na channels is kinetically and structurally distinct from fast inactivation. Whereas structures that participate in fast inactivation are well described and include the cytoplasmic III-IV linker, the nature and location of the slow inactivation gating mechanism rem...

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Autori principali: Struyk, Arie F., Cannon, Stephen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229532/
https://ncbi.nlm.nih.gov/pubmed/12356853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028672
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