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On the Structural Basis for Size-selective Permeation of Organic Cations through the Voltage-gated Sodium Channel : Effect of Alanine Mutations at the DEKA Locus on Selectivity, Inhibition by Ca(2+) and H(+), and Molecular Sieving
Recent evidence indicates that ionic selectivity in voltage-gated Na(+) channels is mediated by a small number of residues in P-region segments that link transmembrane elements S5 and S6 in each of four homologous domains denoted I, II, III, and IV. Important determinants for this function appear to...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
The Rockefeller University Press
1997
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2229404/ https://ncbi.nlm.nih.gov/pubmed/9382897 |
| Tagiau: |
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