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Mechanism of Ion Permeation in Mammalian Voltage-Gated Sodium Channels.

Recent determination of the crystal structures of bacterial voltage-gated sodium (NaV) channels have raised hopes that modeling of the mammalian counterparts could soon be achieved. However, there are substantial differences between the pore domains of the bacterial and mammalian NaV channels, which...

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Autori principali: Somayeh Mahdavi, Serdar Kuyucak
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2015-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4537306?pdf=render
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