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Anomalous Effect of Permeant Ion Concentration on Peak Open Probability of Cardiac Na(+) Channels

Human heart Na(+) channels were expressed transiently in both mammalian cells and Xenopus oocytes, and Na(+) currents measured using 150 mM intracellular Na(+). Decreasing extracellular permeant ion concentration decreases outward Na(+) current at positive voltages while increasing the driving force...

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Detalhes bibliográficos
Main Authors: Townsend, Claire, Hartmann, Hali A., Horn, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229355/
https://ncbi.nlm.nih.gov/pubmed/9234167
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