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Effect of Alkali Metal Cations on Slow Inactivation of Cardiac Na(+) Channels

Human heart Na(+) channels were expressed transiently in both mammalian cells and Xenopus oocytes, and Na(+) currents measured using 150 mM intracellular Na(+). The kinetics of decaying outward Na(+) current in response to 1-s depolarizations in the F1485Q mutant depends on the predominant cation in...

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Bibliographic Details
Main Authors: Townsend, Claire, Horn, Richard
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229358/
https://ncbi.nlm.nih.gov/pubmed/9234168
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