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Characterization of guanylate cyclase activity in single retinal rod outer segments
cGMP mediates vertebrate phototransduction by directly gating cationic channels on the plasma membrane of the photoreceptor outer segment. This second messenger is produced by a guanylate cyclase and hydrolyzed by a light-activated cGMP-phosphodiesterase. Both of these enzyme activities are Ca2+ sen...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1995
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2229293/ https://ncbi.nlm.nih.gov/pubmed/8648296 |
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