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Characterization of guanylate cyclase activity in single retinal rod outer segments

cGMP mediates vertebrate phototransduction by directly gating cationic channels on the plasma membrane of the photoreceptor outer segment. This second messenger is produced by a guanylate cyclase and hydrolyzed by a light-activated cGMP-phosphodiesterase. Both of these enzyme activities are Ca2+ sen...

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Bibliographische Detailangaben
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1995
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229293/
https://ncbi.nlm.nih.gov/pubmed/8648296
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