T cell ignorance in mice to Borna disease virus can be overcome by peripheral expression of the viral nucleoprotein

Infection of neonates with Borna disease virus (BDV) induces severe meningoencephalitis and neurological disorder in wild-type but not in β(2)-microglobulin-deficient mice of strain MRL (H-2(k)). Temporary in vivo depletion of CD8(+) T cells delayed BDV-induced disease for several weeks. Depletion o...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Hausmann, Jürgen, Hallensleben, Wiebke, de la Torre, Juan Carlos, Pagenstecher, Axel, Zimmermann, Christine, Pircher, Hanspeter, Staeheli, Peter
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1999
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449769/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.17.9769
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