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T cell ignorance in mice to Borna disease virus can be overcome by peripheral expression of the viral nucleoprotein

Infection of neonates with Borna disease virus (BDV) induces severe meningoencephalitis and neurological disorder in wild-type but not in β(2)-microglobulin-deficient mice of strain MRL (H-2(k)). Temporary in vivo depletion of CD8(+) T cells delayed BDV-induced disease for several weeks. Depletion o...

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Detalhes bibliográficos
Main Authors: Hausmann, Jürgen, Hallensleben, Wiebke, de la Torre, Juan Carlos, Pagenstecher, Axel, Zimmermann, Christine, Pircher, Hanspeter, Staeheli, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22285/
https://ncbi.nlm.nih.gov/pubmed/10449769
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