Receptor downregulation and desensitization enhance the information processing ability of signalling receptors

BACKGROUND: In addition to initiating signaling events, the activation of cell surface receptors also triggers regulatory processes that restrict the duration of signaling. Acute attenuation of signaling can be accomplished either via ligand-induced internalization of receptors (endocytic downregula...

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Detaylı Bibliyografya
Asıl Yazarlar: Shankaran, Harish, Wiley, H Steven, Resat, Haluk
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228318/
https://ncbi.nlm.nih.gov/pubmed/17996096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-1-48
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