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Receptor downregulation and desensitization enhance the information processing ability of signalling receptors

BACKGROUND: In addition to initiating signaling events, the activation of cell surface receptors also triggers regulatory processes that restrict the duration of signaling. Acute attenuation of signaling can be accomplished either via ligand-induced internalization of receptors (endocytic downregula...

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Détails bibliographiques
Auteurs principaux: Shankaran, Harish, Wiley, H Steven, Resat, Haluk
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228318/
https://ncbi.nlm.nih.gov/pubmed/17996096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-1-48
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