Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoids

BACKGROUND: Glucocorticoids (GC's) play an integral role in treatment strategies designed to combat various forms of hematological malignancies. GCs also are powerful inhibitors of the immune system, through regulation of appropriate cytokines and by causing apoptosis of immature thymocytes. By...

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Bibliografski detalji
Glavni autori: Miller, Aaron L, Komak, Spogmai, Webb, M Scott, Leiter, Edward H, Thompson, E Brad
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Primary Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228275/
https://ncbi.nlm.nih.gov/pubmed/18045478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-7-18
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