Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoids

BACKGROUND: Glucocorticoids (GC's) play an integral role in treatment strategies designed to combat various forms of hematological malignancies. GCs also are powerful inhibitors of the immune system, through regulation of appropriate cytokines and by causing apoptosis of immature thymocytes. By...

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Bibliographic Details
Main Authors: Miller, Aaron L, Komak, Spogmai, Webb, M Scott, Leiter, Edward H, Thompson, E Brad
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
Subjects:
Primary Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228275/
https://ncbi.nlm.nih.gov/pubmed/18045478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-7-18
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