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Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoids

BACKGROUND: Glucocorticoids (GC's) play an integral role in treatment strategies designed to combat various forms of hematological malignancies. GCs also are powerful inhibitors of the immune system, through regulation of appropriate cytokines and by causing apoptosis of immature thymocytes. By...

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Detalhes bibliográficos
Main Authors: Miller, Aaron L, Komak, Spogmai, Webb, M Scott, Leiter, Edward H, Thompson, E Brad
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228275/
https://ncbi.nlm.nih.gov/pubmed/18045478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-7-18
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