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RNA polymerase II transcription is required for human papillomavirus type 16 E7- and hydroxyurea-induced centriole overduplication

Aberrant centrosome numbers are detected in virtually all human cancers where they can contribute to chromosomal instability by promoting mitotic spindle abnormalities. Despite their widespread occurrence, the molecular mechanisms that underlie centrosome amplification are only beginning to emerge....

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Hlavní autoři: Duensing, Anette, Liu, Ying, Spardy, Nicole, Bartoli, Kristen, Tseng, Michelle, Kwon, Jeong-Ah, Teng, Xiaoyi, Duensing, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228273/
https://ncbi.nlm.nih.gov/pubmed/16819507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209782
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