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A Bayesian Approach to Copy-Number–Polymorphism Analysis in Nuclear Pedigrees

Segmental copy-number polymorphisms (CNPs) represent a significant component of human genetic variation and are likely to contribute to disease susceptibility. These potentially multiallelic and highly polymorphic systems present new challenges to family-based genetic-analysis tools that commonly as...

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Detalhes bibliográficos
Main Authors: Kosta, Konstantina , Sabroe, Ian , Göke, Jonathan , Nibbs, Robert J. , Tsanakas, John , Whyte, Moira K. , Teare, M. Dawn 
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Human Genetics 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2227930/
https://ncbi.nlm.nih.gov/pubmed/17847005
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