Llwytho...

Cyclin-dependent kinase 2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication

Cyclin-dependent kinase 2 (CDK2) has been proposed to function as a master regulator of centrosome duplication. Using mouse embryonic fibroblasts (MEFs) in which Cdk2 has been genetically deleted, we show here that CDK2 is not required for normal centrosome duplication, maturation and bipolar mitoti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Duensing, Anette, Liu, Ying, Tseng, Michelle, Malumbres, Marcos, Barbacid, Mariano, Duensing, Stefan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225596/
https://ncbi.nlm.nih.gov/pubmed/16331279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209310
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