Specificity of DNA-binding by the FAX-1 and NHR-67 nuclear receptors of Caenorhabditis elegans is partially mediated via a subclass-specific P-box residue

BACKGROUND: The nuclear receptors of the NR2E class play important roles in pattern formation and nervous system development. Based on a phylogenetic analysis of DNA-binding domains, we define two conserved groups of orthologous NR2E genes: the NR2E1 subclass, which includes C. elegans nhr-67, Droso...

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Detalhes bibliográficos
Main Authors: DeMeo, Stephen D, Lombel, Rebecca M, Cronin, Melissa, Smith, Eric L, Snowflack, Danielle R, Reinert, Kristy, Clever, Sheila, Wightman, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225407/
https://ncbi.nlm.nih.gov/pubmed/18179707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-2
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