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The Role of Nuclear Receptor NHR-64 in Fat Storage Regulation in Caenorhabditis elegans

Nuclear hormone receptors (NHRs) play vital roles in the regulation of metabolism, reproduction, and development. We found that inactivation of a C. elegans HNF4 homologue nhr-64 by RNA interference (RNAi) suppresses low fat stores in stearoyl-CoA desaturase-deficient fat-6;fat-7 double mutants and...

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Autores principales: Liang, Bin, Ferguson, Kim, Kadyk, Lisa, Watts, Jennifer L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845610/
https://ncbi.nlm.nih.gov/pubmed/20360843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009869
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