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Removal of a Single N-Linked Glycan in Human Immunodeficiency Virus Type 1 gp120 Results in an Enhanced Ability To Induce Neutralizing Antibody Responses

Glycans on human immunodeficiency virus (HIV) envelope protein play an important role in infection and evasion from host immune responses. To examine the role of specific glycans, we introduced single or multiple mutations into potential N-linked glycosylation sites in hypervariable regions (V1 to V...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Yun, Cleveland, Bradley, Klots, Igor, Travis, Bruce, Richardson, Barbra A., Anderson, David, Montefiori, David, Polacino, Patricia, Hu, Shiu-Lok
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224603/
https://ncbi.nlm.nih.gov/pubmed/17959660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01691-07
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