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The Antiapoptotic Herpes Simplex Virus Glycoprotein J Localizes to Multiple Cellular Organelles and Induces Reactive Oxygen Species Formation

The Us5 gene of herpes simplex virus (HSV) encodes glycoprotein J (gJ). The only previously reported function of gJ was its ability to inhibit apoptosis. However, the mechanism by which gJ prevents apoptosis is not understood, and it is not known whether gJ mediates additional cellular effects. In t...

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Detalhes bibliográficos
Main Authors: Aubert, Martine, Chen, Zheng, Lang, Robin, Dang, Chung H., Fowler, Carla, Sloan, Derek D., Jerome, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224592/
https://ncbi.nlm.nih.gov/pubmed/17959661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01341-07
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