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Cation-Independent Mannose 6-Phosphate Receptor Blocks Apoptosis Induced by Herpes Simplex Virus 1 Mutants Lacking Glycoprotein D and Is Likely the Target of Antiapoptotic Activity of the Glycoprotein

Herpes simplex virus 1 mutants lacking the gene encoding glycoprotein D (gD) and the gD normally present in the envelope of the virus (gD(−/−) stocks) or mutants lacking the gD gene but containing trans-induced gD in their envelopes (gD(−/+)) cause apoptosis in human SK-N-SH cells. The gD(−/−) virio...

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Autors principals: Zhou, Guoying, Roizman, Bernard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC136186/
https://ncbi.nlm.nih.gov/pubmed/12021353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.12.6197-6204.2002
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