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Herpes Simplex Virus Remodels T-Cell Receptor Signaling, Resulting in p38-Dependent Selective Synthesis of Interleukin-10

Herpes simplex virus (HSV)-specific T cells are essential for viral clearance. However, T cells do not prevent HSV latent infection or reactivation, suggesting that HSV has the potential to modulate T-cell function. T-cell receptor (TCR) stimulation is a potent and specific means of activating T cel...

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Detalhes bibliográficos
Main Authors: Sloan, Derek D., Jerome, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169026/
https://ncbi.nlm.nih.gov/pubmed/17804501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01111-07
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