Engineered Disulfide Bonds in Herpes Simplex Virus Type 1 gD Separate Receptor Binding from Fusion Initiation and Viral Entry

Glycoprotein D (gD) is the receptor binding protein of herpes simplex virus (HSV) and binds to at least two distinct protein receptors, herpesvirus entry mediator (HVEM) and nectin-1. While both receptor binding regions are found within the first 234 amino acids, a crystal structure shows that the C...

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Dettagli Bibliografici
Autori principali: Lazear, Eric, Carfi, Andrea, Whitbeck, J. Charles, Cairns, Tina M., Krummenacher, Claude, Cohen, Gary H., Eisenberg, Roselyn J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224591/
https://ncbi.nlm.nih.gov/pubmed/18032483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02192-07
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