The Membrane-Proximal Region (MPR) of Herpes Simplex Virus gB Regulates Association of the Fusion Loops with Lipid Membranes

Glycoprotein B (gB), gD, and gH/gL constitute the fusion machinery of herpes simplex virus (HSV). Prior studies indicated that fusion occurs in a stepwise fashion whereby the gD/receptor complex activates the entire process, while gH/gL regulates the fusion reaction carried out by gB. Trimeric gB is...

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Hlavní autoři: Shelly, Spencer S., Cairns, Tina M., Whitbeck, J. Charles, Lou, Huan, Krummenacher, Claude, Cohen, Gary H., Eisenberg, Roselyn J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Microbiology 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509434/
https://ncbi.nlm.nih.gov/pubmed/23170000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00429-12
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