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Lymphocytoid Choriomeningitis Virus Activates Plasmacytoid Dendritic Cells and Induces a Cytotoxic T-Cell Response via MyD88

Toll-like receptors (TLRs) and retinoic acid-inducible gene I-like helicases (RLHs) are two major machineries recognizing RNA virus infection of innate immune cells. Intracellular signaling for TLRs and RLHs is mediated by their cytoplasmic adaptors, i.e., MyD88 or TRIF and IPS-1, respectively. In t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jung, Andreas, Kato, Hiroki, Kumagai, Yutaro, Kumar, Himanshu, Kawai, Taro, Takeuchi, Osamu, Akira, Shizuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224366/
https://ncbi.nlm.nih.gov/pubmed/17942529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01640-07
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