Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration

Tissue injury and the healing response lead to the release of endogenous danger signals including Toll-like receptor (TLR) and interleukin-1 receptor, type 1 (IL-1R1) ligands, which modulate the immune microenvironment. Because TLRs and IL-1R1 have been shown to influence the repair process of vario...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Martino, Mikaël M., Maruyama, Kenta, Kuhn, Gisela A., Satoh, Takashi, Takeuchi, Osamu, Müller, Ralph, Akira, Shizuo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804175/
https://ncbi.nlm.nih.gov/pubmed/27001940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11051
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