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Three-dimensional cellular microarray for high-throughput toxicology assays

We have developed a miniaturized 3D cell-culture array (the Data Analysis Toxicology Assay Chip or DataChip) for high-throughput toxicity screening of drug candidates and their cytochrome P450-generated metabolites. The DataChip consists of human cells encapsulated in collagen or alginate gels (as s...

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Autors principals: Lee, Moo-Yeal, Kumar, R. Anand, Sukumaran, Sumitra M., Hogg, Michael G., Clark, Douglas S., Dordick, Jonathan S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224231/
https://ncbi.nlm.nih.gov/pubmed/18160535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708756105
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