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Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation
A key energy-saving adaptation to chronic hypoxia that enables cardiomyocytes to withstand severe ischemic insults is hibernation, i.e., a reversible arrest of contractile function. Whereas hibernating cardiomyocytes represent the critical reserve of dysfunctional cells that can be potentially rescu...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2224202/ https://ncbi.nlm.nih.gov/pubmed/18162550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707778105 |
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