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Laminopathic mutations interfere with the assembly, localization, and dynamics of nuclear lamins

Lamins are nuclear intermediate filament proteins and the major building blocks of the nuclear lamina. Besides providing nuclear shape and mechanical stability, lamins are required for chromatin organization, transcription regulation, DNA replication, nuclear assembly, nuclear positioning, and apopt...

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Detalhes bibliográficos
Main Authors: Wiesel, Naama, Mattout, Anna, Melcer, Shai, Melamed-Book, Naomi, Herrmann, Harald, Medalia, Ohad, Aebi, Ueli, Gruenbaum, Yosef
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224182/
https://ncbi.nlm.nih.gov/pubmed/18162544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708974105
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