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Laminopathic mutations interfere with the assembly, localization, and dynamics of nuclear lamins
Lamins are nuclear intermediate filament proteins and the major building blocks of the nuclear lamina. Besides providing nuclear shape and mechanical stability, lamins are required for chromatin organization, transcription regulation, DNA replication, nuclear assembly, nuclear positioning, and apopt...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2224182/ https://ncbi.nlm.nih.gov/pubmed/18162544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708974105 |
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