Nitric oxide enhancement of melphalan-induced cytotoxicity.

The effects of the diatomic radical, nitric oxide (NO), on melphalan-induced cytotoxicity in Chinese hamster V79 and human MCF-7 breast cancer cells were studied using clonogenic assays. NO delivered by the NO-releasing agent (C2H5)2N[N(O)NO]- Na+ (DEA/NO; 1 mM) resulted in enhancement of melphalan-...

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Bibliographic Details
Main Authors: Cook, J. A., Krishna, M. C., Pacelli, R., DeGraff, W., Liebmann, J., Mitchell, J. B., Russo, A., Wink, D. A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224050/
https://ncbi.nlm.nih.gov/pubmed/9252199
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