Nitric oxide mediates interleukin-1-induced cellular cytotoxicity in the rat ovary. A potential role for nitric oxide in the ovulatory process.

Treatment of primary cultures of rat ovarian dispersates with IL-1 beta results in morphologic and cytotoxic changes, thought to reflect tissue remodeling events associated with ovulation. We examined the role that the free radical nitric oxide plays in this process and report that IL-1 beta induces...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Ellman, C, Corbett, J A, Misko, T P, McDaniel, M, Beckerman, K P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504698/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116930
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