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Pharmacokinetics and Pharmacodynamics of Piperaquine in a Murine Malaria Model

Piperaquine (PQ) is an important partner in antimalarial treatment strategies. However, there is a paucity of detailed preclinical and pharmacokinetic data to link PQ serum concentrations and toxicity or efficacy. The aim of this study was to investigate the pharmacokinetics and pharmacodynamics of...

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Hlavní autoři: Moore, Brioni R., Batty, Kevin T., Andrzejewski, Christopher, Jago, Jeffrey D., Page-Sharp, Madhu, Ilett, Kenneth F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223920/
https://ncbi.nlm.nih.gov/pubmed/17984231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00878-07
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